

He has published new surgical biomarker studies that are the first to use personalized proteomics to precisely diagnose and treat otherwise problematic retinal diseases. Mahajan is among only a handful of surgeons to perform human gene therapy for retinal disease. He has identified safer approaches for vitreoretinal surgery in children and adults, and provides second opinions for complex cases. He has developed enhanced surgeries for complex cases of retinal detachment, macular hole, macular edema, diabetes, macular degeneration, proliferative vitreoretinopathy, optic maculopathy, uveitis, and others. Mahajan has trained numerous surgical fellows that now operate around the world. Using translational proteomics, Mahajan’s multidisciplinary team is developing new precision health approaches using molecular biomarkers to diagnose retinal disease, select personalized therapies, and decode the anatomic structures of the human eye. They have also created in vivo models for diabetic retinopathy and uveitis. Mahajan and his team performed the first CRISPR gene editing therapy for eye disease in human stem cells. His research team discovered the first gene to cause non syndromic uveitis and is now using protein crystallography to design therapeutic inhibitors for calpain-5. He directs the NIH-funded Molecular Surgery and Omics Laboratory that uses high-throughput methods in genomics, proteomics, and phenomics to identify molecules involved in vitreoretinal disease. Mahajan is a Professor and vitreoretinal surgeon and scientist in the Department of Ophthalmology at Stanford University.

“As one of the earliest pilot locations for Lumata’s service, I’ve seen the potential value for my patients firsthand.

Steven Ryder, Retina Surgeon at Horizon Eye Care Lumata delivers with brilliance and compassion.” There is no denying that high-quality eye care requires time, open dialogue, and collaboration. “Over the past year, I have watched Lumata provide outstanding service to (and shine their light for) hundreds of my retina patients. Ashkan Abbey, Director of Clinical Research at Texas Retina Associates The engagement with my retina patients has been tremendous.”

“I have been fortunate to be among the first in the country to pilot Lumata’s service. Leila Vajzovic, Surgical & Medical Retinal Specialist & Director at Duke Eye Center “This is a huge unmet need for ophthalmology.”
